2001•PubMedRequires access

[A study on beta-lactamase activity of biofilm Escherichia coli].

Ping He, Li N, Li S

Abstract

OBJECTIVE: To investigate the mechanism of drug resistance of biofilm escherichia coli. METHODS: The model of escherichia coli biofilm was established with the flat-board method. And the biofilm was confirmed by scanning electron microscopy. The beta-lactamase activities were quantitated, in escherichia coli, biofilm escherichia coli, biofilm escherichia coli induced by impenem or cefoxitin. RESULTS: The beta-lactamase activity of biofilm escherichia coli was 2.16 times as much as that of escherichia coli planctonically, and the beta-lactamase activities of biofilm escherichia coli induceded by impenem or cefoxitin were 1.30 and 1.05 times as much as those of biofilm escherichia coli, respectively. CONCLUSION: The drug resistance to antibiotics of biofilm escherichia coli was related to the production of beta-lactamase.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Escherichia coli, Biofilm, Microbiology, Cefoxitin, Escherichia, Enterobacteriaceae, Chemistry, Biology