Establishment of animal models of peri-implantitis in dogs

Objective To establish experimental peri-implantitis animal models in beagle dogs.Methods Six beagle dogs about one year old with good general health would be used.The silk ligatures would be forced into a position directly apical to the gingival margin of teeth for 3 months in order to establish experimental periodontitis,then implants were placed into the dogs in order to establish peri-implantitis,and the clinical status would be checked from the experimental implants,at 1 st,3 rd,7 th,14 th,30 th,60 th,and 90 th days.Results All the experimental implants demonstrated significantly experimental peri-implantitis similar to human peri-implantitis,but the severity was different.Conclusions The experimental peri-implantitis animal models in beagle dogs are significant animal models,which have a high success rate and is helpful to the clinical research.