Studies of correlation between Serum Resistin and Microalbuminuria in Diabetic Subjects with Metabolic Syndrome

Objective To detect serum resistin level in type 2 diabetes mellitus(T2DM)with metabolic syndrome(MS)and the relationship between the serum resistin level and microalbuminuria(MAU).Methods 83 hospital patients with T2DM were selected randomly and divided into two groups by with or without MS.MS group(45 cases)and T2DM group(38 cases),33 healthy subjects were chosen as normal control group(NC.) All cases must be recorded clinical data such as height,weight,waist circumference(WC)and monitored the index of laboratory data such as fasting plasma glucose(FPG),fasting insulin(FIns),serum lipid and serum resistin level,etc.24-hour urine sample was reserved for MAU testing.Results The serum resistin level of MS subjects was significantly higher than that of T2DM and NC subjects(P0.01);which of T2DM group was higher than that of NC group(P0.01.) Positive correlations were indicated between resistin and other items,such as Homeostasis model assessment-insulin resistance index(Homa-IR),MAU in MS group(P0.01);there were positive correlations between resistin and Homa-IR,MAU in T2DM group(P0.05).Conclusions Serum resistin in diabetic subjects with MS was significantly higher than that of diabetic without it and healthy subjects,there was positive correlation between resistin and MAU.