2011Journal of Tropical MedicineOpen access

Clinical distribution and drug resistance of Acinetobacter baumannii

Jun Ke

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Abstract

Objective To investigate the isolation rate,distribution and trend of drug resistance of Acinetobacter baumannii from 2004 to 2010.Methods French bioMerieux VITEK32 bacterial identification system was used for identification.The K-B method was used for drug sensitivity test and the results of drug sensitivity test was determined using the CLSI /NCCLs standard.Results 26 670 specimens were analyzed from 2004 to 2010.7 065 bacterial strains isolated from the positive samples,of which 6.67%(471 /7 065) was Acinetobacter baumannii strains.The isolation rate of Acinetobacter baumannii was 1.77%.409 strains were isolated from sputum samples accounted for 86.83% of the total number of Acinetobacter baumannii isolates.The isolation rate is the highest in the ICU ward(49.3%).Acinetobacter baumannii resistance to antimicrobial drugs is generally higher,and showing a trend of increasing,and some exhibit multidrug resistance characteristics.Conclusion There is a trend of increase in drug resistance in Acinetobacter baumannii.We should pay attention to clinical Acinetobacter baumannii infection and separation;beware of multi-resistance in Acinetobacter baumannii nosocomial infections and outbreaks.

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Objective To investigate the isolation rate,distribution and trend of drug resistance of Acinetobacter baumannii from 2004 to 2010.Methods French bioMerieux VITEK32 bacterial identification system was used for identification.The K-B method was used for drug sensitivity test and the results of drug sensitivity test was determined using the CLSI /NCCLs standard.Results 26 670 specimens were analyzed from 2004 to 2010.7 065 bacterial strains isolated from the positive samples,of which 6.67%(471 /7 065) was Acinetobacter baumannii strains.The isolation rate of Acinetobacter baumannii was 1.77%.409 strains were isolated from sputum samples accounted for 86.83% of the total number of Acinetobacter baumannii isolates.The isolation rate is the highest in the ICU ward(49.3%).Acinetobacter baumannii resistance to antimicrobial drugs is generally higher,and showing a trend of increasing,and some exhibit multidrug resistance characteristics.Conclusion There is a trend of increase in drug resistance in Acinetobacter baumannii.We should pay attention to clinical Acinetobacter baumannii infection and separation;beware of multi-resistance in Acinetobacter baumannii nosocomial infections and outbreaks.

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Available abstract

Objective To investigate the isolation rate,distribution and trend of drug resistance of Acinetobacter baumannii from 2004 to 2010.Methods French bioMerieux VITEK32 bacterial identification system was used for identification.The K-B method was used for drug sensitivity test and the results of drug sensitivity test was determined using the CLSI /NCCLs standard.Results 26 670 specimens were analyzed from 2004 to 2010.7 065 bacterial strains isolated from the positive samples,of which 6.67%(471 /7 065) was Acinetobacter baumannii strains.The isolation rate of Acinetobacter baumannii was 1.77%.409 strains were isolated from sputum samples accounted for 86.83% of the total number of Acinetobacter baumannii isolates.The isolation rate is the highest in the ICU ward(49.3%).Acinetobacter baumannii resistance to antimicrobial drugs is generally higher,and showing a trend of increasing,and some exhibit multidrug resistance characteristics.Conclusion There is a trend of increase in drug resistance in Acinetobacter baumannii.We should pay attention to clinical Acinetobacter baumannii infection and separation;beware of multi-resistance in Acinetobacter baumannii nosocomial infections and outbreaks.

Key concepts: Acinetobacter baumannii, Acinetobacter, Microbiology, Drug resistance, Multiple drug resistance, Antibiotic resistance, Medicine, Isolation (microbiology)

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