Early Diagnostic Value of Computed Tomography Angiography for Acute Kawasaki Disease

Objective To explore the clinical value of computed tomography angiography in the diagnosis of Kawasaki disease at acute stage.Methods 35 KD cases,including 22 males and 13 females,whose ages of onset ranging from 6 months to 8 years old,on average(2.0±1.6) years old,received Real-Time Three-Dimensional Echocardiography(RT3DE) and cardiac CTA in order to observe the coronary.Then data collected by using the two methods were compared and analyzed.Results CTA showed the number of coronary artery lesion was 14 cases involving 15 coronary arteries,among which there was 1 left coronary artery aneurysm,4 with uneven thickness,7 dilated coronary arteries,2 dilated right coronary arteries and 1 right coronary artery aneurysm.RT3DE showed that the number of coronary artery lesion was 8 cases involving 9 coronary arteries,among which there was 1 left coronary artery aneurysm,6 dilated left coronary arteries,1 right coronary artery aneurysm and 1 dilated right coronary artery.There was no significant difference between the two methods(P0.05).However,there was significant correlation in uneven thickness of coronary artery with the two methods(P0.05).The correlation between RT3DE and CTA in left and right coronary artery was significantly positive(r=0.95,r=0.90,respectively,P0.01).Conclusion RT3DE only can detect the lesions in the initial period of coronary artery,but it is not clear as good as CTA.CTA can demonstrate the whole picture of coronary and precisely get the message of coronary appearance.It is a more accurate evaluation of KD acute phase of coronary artery lesions.It has a big clinical significance for the early diagnosis of Kawasaki disease coronary arteries.