Evaluation of early trachea cannula mechanical ventilation as a treatment of severe acute left ventricular failures

Objective To evaluate the effectiveness of early trachea cannula mechanical ventilation in treating severe acute left ventricular failures.Methods One hundred and twelve patients with severe acute left ventricular failures were divided into two groups:early mechanical ventilation group(n=36)and conventional mechanical ventilation group(n=76).The time of symptomatic relief,duration of mechanical ventilation,blood-brain natriuretic peptide(BNP),inpatient time and hospital mortality of the two groups were compared.Results Compared with conventional mechanical ventilation group,early mechanical ventilation group's time of symptomatic relief decreased significantly[(4.3±1.1)h vs(7.3±2.1)h,P0.01];its duration of mechanical ventilation[(66.4±12.4)h vs(78.3±15.6)h,P0.01]and BNP concentration[(452±112)ng/L vs(634±232)ng/L,P0.01]also decreased.7 days after hospitalization,early mechanical ventilation group's inpatient time[(15.3±5.1)d vs(21.1±7.1)d,P0.01]and hospital mortality(8.3% vs 27.6%,P0.05)both decreased.Conclusions Early trachea cannula mechanical ventilation can decrease the time of symptomatic relief,duration of mechanical ventilation,inpatient time and hospital mortality of the patients with severe acute left ventricular failure.