2011Fine and Specialty ChemicalsRequires access

Research advancements of modification ofγ-polyglutamic acid and their highly added value applications

Chen Yi-ben

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Abstract

γ-Polyglutamic acid(γ-PGA) is a amino-acid polymer containing D-and L-glutamic acid units. This polymer is water soluble,biodegradable,edible,biocompatible,non-toxic and safety.γ-PGA contains hydroxyl group and amino group in its unit structure,and a special kind of polar polymer could be obtained by introduction of same group.In this paper,several methods commonly used forγ-polyglutamic acid modification and their highly added value applications of modifiedγ-polyglutamic acid in biomedicine were summarized at present.

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What this paper is about

γ-Polyglutamic acid(γ-PGA) is a amino-acid polymer containing D-and L-glutamic acid units. This polymer is water soluble,biodegradable,edible,biocompatible,non-toxic and safety.γ-PGA contains hydroxyl group and amino group in its unit structure,and a special kind of polar polymer could be obtained by introduction of same group.In this paper,several methods commonly used forγ-polyglutamic acid modification and their highly added value applications of modifiedγ-polyglutamic acid in biomedicine were summarized at present.

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Available abstract

γ-Polyglutamic acid(γ-PGA) is a amino-acid polymer containing D-and L-glutamic acid units. This polymer is water soluble,biodegradable,edible,biocompatible,non-toxic and safety.γ-PGA contains hydroxyl group and amino group in its unit structure,and a special kind of polar polymer could be obtained by introduction of same group.In this paper,several methods commonly used forγ-polyglutamic acid modification and their highly added value applications of modifiedγ-polyglutamic acid in biomedicine were summarized at present.

Key concepts: Polyglutamic acid, Chemistry, Polymer, Biocompatible material, Organic chemistry, Polymer chemistry, Biochemistry, Biomedical engineering

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