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[Influence of embryo transfer depth on in vitro fertilization and embryo transfer outcomes].

Zhao Xiao-hui, Xueru Song, Xiao-lin Sui, Xiaohong Bai

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Abstract

OBJECTIVE: To investigate the influence of transfer distance from the fundus on clinical pregnancy rate and implantation rate in in vitro fertilization and embryo transfer. METHODS: A total of 98 patients (108 cycles) undergoing ultrasound-guided embryo transfer were divided into two groups according to the distance between the tip of catheter and the uterine fundus: group A: > or = 5 - < 10 mm, group B: > or = 10 - < or = 15 mm. RESULTS: Clinical pregnancy rate and implantation rate were significantly higher in group B compared with group A [44 % (23/52) vs 25% (14/56), 24% (28/115) vs 14% (17/121), P < 0.05]. The multiple pregnancy rate, ectopic rate and miscarriage rate were similar in the two groups (P > 0.05). CONCLUSION: The depth of the embryo replacement into the uterine cavity may influence pregnancy rate and implantation rate.

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What this paper is about

OBJECTIVE: To investigate the influence of transfer distance from the fundus on clinical pregnancy rate and implantation rate in in vitro fertilization and embryo transfer. METHODS: A total of 98 patients (108 cycles) undergoing ultrasound-guided embryo transfer were divided into two groups according to the distance between the tip of catheter and the uterine fundus: group A: > or = 5 - < 10 mm, group B: > or = 10 - < or = 15 mm. RESULTS: Clinical pregnancy rate and implantation rate were significantly higher in group B compared with group A [44 % (23/52) vs 25% (14/56), 24% (28/115) vs 14% (17/121), P < 0.05]. The multiple pregnancy rate, ectopic rate and miscarriage rate were similar in the two groups (P > 0.05). CONCLUSION: The depth of the embryo replacement into the uterine cavity may influence pregnancy rate and implantation rate.

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Available abstract

OBJECTIVE: To investigate the influence of transfer distance from the fundus on clinical pregnancy rate and implantation rate in in vitro fertilization and embryo transfer. METHODS: A total of 98 patients (108 cycles) undergoing ultrasound-guided embryo transfer were divided into two groups according to the distance between the tip of catheter and the uterine fundus: group A: > or = 5 - < 10 mm, group B: > or = 10 - < or = 15 mm. RESULTS: Clinical pregnancy rate and implantation rate were significantly higher in group B compared with group A [44 % (23/52) vs 25% (14/56), 24% (28/115) vs 14% (17/121), P < 0.05]. The multiple pregnancy rate, ectopic rate and miscarriage rate were similar in the two groups (P > 0.05). CONCLUSION: The depth of the embryo replacement into the uterine cavity may influence pregnancy rate and implantation rate.

Key concepts: Embryo transfer, In vitro fertilisation, Embryo, Pregnancy rate, Miscarriage, Andrology, Pregnancy, Gynecology

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