Application of Spray Drying Technique to Preparation of Protein and Peptide-loaded Microspheres: a Review
He Ying
Abstract
He Ying
Abstract
According to different kinds of common carrier materials: PLA,PLGA and chitosan,the advances in application of spray drying technique to preparation of protein-and peptide-loaded microspheres were reviewed classifiedly.And the characteristics of major spray drying techniques,such as solution/spraydrying,emulsion/spray-drying,spray freeze drying,spray freezing into liquid and cryogenic spray extraction,were introduced and compared.
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According to different kinds of common carrier materials: PLA,PLGA and chitosan,the advances in application of spray drying technique to preparation of protein-and peptide-loaded microspheres were reviewed classifiedly.And the characteristics of major spray drying techniques,such as solution/spraydrying,emulsion/spray-drying,spray freeze drying,spray freezing into liquid and cryogenic spray extraction,were introduced and compared.
Key concepts: Spray drying, Microsphere, Chromatography, Materials science, Emulsion, PLGA, Freeze-drying, Chitosan