Assessment of left ventricular function in dogs after acute ischemia-reperfusion by two-dimensional speckle tracking imaging

Objective To assess the value of isovolumic contraction acceleration(ICA) in evaluation of canine left ventricular function by two-dimensional speckle tracking imaging(STI). Methods Acute myocardial infarction and reperfusion model was established in 14 dogs. Echocardiography was applied on baseline,immediately after ligation,30 min,120 min,180 min after ligation and immediately after reperfusion,60 min,120 min after reperfusion. STI was performed to measure the left ventricular(LV) radial and circumferential ICA. Results The radial and circumferential ICA of ischemia segments was decreased 30 min after infarction. It was gradually decreased with the prolongation of infarction time(P0.05). After reperfusion, the ICA was gradually increased(P0.05). Conclusion Two-dimensional STI technology could quantitatively evaluate segmental wall motion abnormalities in dogs after acute ischemia-reperfusion,which provids useful information for evaluation of LV systolic function.