2003Journal of OncologyRequires access

Vinorelbine plus Cisplatin for The Treatmant of 30 Cases with Advanced Breast Cancer

Ren Hai-hua

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Abstract

To investigate the effect o f Vinorelbine plus Cisplatin(NP)regimen for advanced breast cancer.Thirty cases with breast cancer stageⅢ~Ⅳwere treated with NP regimen(NVB25mg/m 2 iv d1,8,DDP was35mg/m 2 iv d1~3).Eighteen cases were primary treated,the others were previously trea ted.The response rate(RR)of primary treated group was72%(13/18),while t hat of previously treated group was50%(6/12).The overall RR was63%.The medium du ration of response and medium survival time were9months and17months,respectively .[Conclusions]NP regimen is effective in treating advameed breast cancer and gen erally well tolerated,further studies are required.

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What this paper is about

To investigate the effect o f Vinorelbine plus Cisplatin(NP)regimen for advanced breast cancer.Thirty cases with breast cancer stageⅢ~Ⅳwere treated with NP regimen(NVB25mg/m 2 iv d1,8,DDP was35mg/m 2 iv d1~3).Eighteen cases were primary treated,the others were previously trea ted.The response rate(RR)of primary treated group was72%(13/18),while t hat of previously treated group was50%(6/12).The overall RR was63%.The medium du ration of response and medium survival time were9months and17months,respectively .[Conclusions]NP regimen is effective in treating advameed breast cancer and gen erally well tolerated,further studies are required.

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Available abstract

To investigate the effect o f Vinorelbine plus Cisplatin(NP)regimen for advanced breast cancer.Thirty cases with breast cancer stageⅢ~Ⅳwere treated with NP regimen(NVB25mg/m 2 iv d1,8,DDP was35mg/m 2 iv d1~3).Eighteen cases were primary treated,the others were previously trea ted.The response rate(RR)of primary treated group was72%(13/18),while t hat of previously treated group was50%(6/12).The overall RR was63%.The medium du ration of response and medium survival time were9months and17months,respectively .[Conclusions]NP regimen is effective in treating advameed breast cancer and gen erally well tolerated,further studies are required.

Key concepts: Vinorelbine, Medicine, Regimen, Cisplatin, Breast cancer, Oncology, Internal medicine, Chemotherapy

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