Research progress on antioxidants against neurotoxicity induced by methylmercury
Zhaofa Xu
Abstract
Zhaofa Xu
Abstract
Brain is the main target organ poisoned by methylmercury,the mechanism of the neurotoxicity is still not quite clear.It was suggested that oxidative damage might play a key role in methylmercury induced neurotoxicity.Antioxidants are a kind of the substances with low toxicity and high bioactivity.In this paper,the mechanisms of neurotoxicity casued by methylmercury and the antagonistic effect of antioxidants were reviewed.
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Brain is the main target organ poisoned by methylmercury,the mechanism of the neurotoxicity is still not quite clear.It was suggested that oxidative damage might play a key role in methylmercury induced neurotoxicity.Antioxidants are a kind of the substances with low toxicity and high bioactivity.In this paper,the mechanisms of neurotoxicity casued by methylmercury and the antagonistic effect of antioxidants were reviewed.
Key concepts: Neurotoxicity, Methylmercury, Chemistry, Pharmacology, Mechanism (biology), Oxidative damage, Toxicity, Antioxidant