Prognosis and clinical observation of statins in the treatment of paroxysmal atrial fibrillation

Objective To investigate the prognosis and clinical efficacy of statins in the treatment of paroxysmal atrial fibrillation.Methods 60 patients with paroxysmal atrial fibrillation in Guanlan People's Hospital of Longhua District in Shenzhen City from March 2011 to January 2012 were randomly divided into treatment group and control group,with 30 cases in each group.The treatment group was treated with Atorvastatin Calcium Tablets,while the control group was treated with traditional treatment of Bayaspirin for anti-platelet aggregation.After 3,6,12 months,the incidence of paroxysmal atrial fibrillation,hs-CRP level,LDL-C level,the patient's readmission rate and disability rate of the two groups were recorded.Results After treatment for 3,6 months,the incidence of paroxysmal atrial fibrillation of the two groups was not statistically significant(P 0.05).However,after treatment for 12 months,during follow-up,the incidence of paroxysmal atrial fibrillation in treatment group(12.8%) was significantly lower than control group(46.2%),the difference was statistically significant different(P 0.05).The hs-CRP and LDL-C level of treatment group were significant lower than those of control group(P 0.05).The readmission rate and disability rate of treatment group were significant lower than those of control group(P 0.05).Conclusion Statins treatment can reduce the relapse of paroxysmal atrial fibrillation,and it is also secure and effective.It is worthy of clinical application.