Comparison of three methods for screening cervical cancer in Southeast Shandong Province

Objective To understand the prevalelnce of cervical cancer in southwest area of Shandong province and compare 3 popular screening tests for cervical cancer.Methods Totally 890 women in southwest area of Shandong were screened for cervical cancer,colposcopy histopathological findings were taken as a golden standard,the Pap smears,liquid-based cytology and naked eye observation supplemented by acetic acid white stain were used and compared.Results The sensitivity,specificity,positive predictive value and negative predictive value of Pap smears for screening cervical intraepithelial lesions were 27.8%,87.5%,29.9%,98.1%;that of liquid based cytology were 79.6%,91.2%,38.4%,99.3% and that of the naked eye observation supplemented by acetic acid white staining were 67.2%,78.5%,9.2%,99.6%.Conclusion Liquid-based cytology possessed the highest value for diagnosis and it can be used as the priority for cervical cancer screening,while macroscopic observation supplemented by acetic acid white staining is simple and suitable for cervical cancer screening in impoverished area.