Value of Serum-Ascites-Albumin Gradient(SAAG) in Diagnosis of Portal Hypertension
LU Xinhua
Abstract
LU Xinhua
Abstract
Objective: To investigate the value of serum-ascites-albumin gradient(SAAG) in diagnosis of portal hypertension.Method:Sixty-eight cases of ascites patients were selected,among which 21 cases were suffering from cirrhosis of liver(group A),10 contracted primary liver cancer without peritonaeum metastasis(group B),5 cases were the patients with dysfunctional cirrhosis of liver complicated with spontaneous bacterial peritonitis(group C),20 were sick with tuberculous peritonitis(group D),and 12 were cancer patients induced ascites(group E).Before treatment,ascites and elbow vein blood were collected by abdominocentesis and venipuncture respectively.Albumin concentration was examined,and SAAG was calculated.Result:SAAG of group A,B and C were higher than that of groups D and E respectively.Group A,B,C were combined as the portal hypertension group,and groups D, E as the non-portal hypertension group.The boundary of SAAG was set ≥11.0 g/L.The sensitivity of the former was 94.4%(34/36),distinctive degree was 96.9%(31/32),and the accurate degree was 95.6%(65/68).Conclusion:SAAG is of great medical significance in diagnosis of portal hypertension and worthy for clinical application.
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Objective: To investigate the value of serum-ascites-albumin gradient(SAAG) in diagnosis of portal hypertension.Method:Sixty-eight cases of ascites patients were selected,among which 21 cases were suffering from cirrhosis of liver(group A),10 contracted primary liver cancer without peritonaeum metastasis(group B),5 cases were the patients with dysfunctional cirrhosis of liver complicated with spontaneous bacterial peritonitis(group C),20 were sick with tuberculous peritonitis(group D),and 12 were cancer patients induced ascites(group E).Before treatment,ascites and elbow vein blood were collected by abdominocentesis and venipuncture respectively.Albumin concentration was examined,and SAAG was calculated.Result:SAAG of group A,B and C were higher than that of groups D and E respectively.Group A,B,C were combined as the portal hypertension group,and groups D, E as the non-portal hypertension group.The boundary of SAAG was set ≥11.0 g/L.The sensitivity of the former was 94.4%(34/36),distinctive degree was 96.9%(31/32),and the accurate degree was 95.6%(65/68).Conclusion:SAAG is of great medical significance in diagnosis of portal hypertension and worthy for clinical application.
Key concepts: Medicine, Ascites, Cirrhosis, Portal hypertension, Gastroenterology, Internal medicine, Albumin, Group B