2009•Sichuan Medical JournalRequires access

The expression and signifcance of E-selectin P-selectin in human gliomas

Zhou You-xin

Abstract

Objective To investigate the expression of E-selectin,P-selectin in gliomas and the relation between the selectins.Methods The expression of E-selectin,P-selectin are detected in paraffin sections by using SP immunohistochemical method.Results ①The positive expression rate of E-selectin and P-selectin in gliomas are significantly higer than in control group(P0.05);②The expression rate of E-selectin in gliomas of grade Ⅰ～Ⅱ are significantly lower than in gliomas of grade Ⅲ～Ⅳ(P0.05).There are no differences of expression of P-selectin between grade Ⅰ～Ⅱand grade Ⅲ～Ⅳ of glioma group(P0.05);③There is no relation between the expression of the two selectins in gilomas.Conclusion E-selectin,P-selectin may be correlated to the oncogenisis and progression of gliomas.

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Key concepts: Selectin, Medicine, L-selectin, P-selectin, E-selectin, Glioma, Immunohistochemistry, Expression (computer science)