A Study on Angiostrongylus cantonensis in Fujian

Objective] To study the characterization of the Angiostrongylus cantonensis in Fujian, find out its effective diagnosis method and treatment . [Methods] To investigate the distribution of A. cantonensis in Fujian,set up an animal model of experimental infection,observe the pathogenic cause, detect the antibodies in the host serum and test the effectiveness of drugs. [Results] There were A.cantonensis in Fujian. The terminal host was Rattus norvegicus and intermediate hosts were Ampullarum crossean and Achatina fulica. The larva infected human and animal through mouth and invaded the central nervous system immediately. 20 days later,the young adult immigrated to the heart and lung,the serum antibody reached to higher levels. 36 days later, the first stage larva was found in the faeces. The Mebendazole and Albendozole were the effective drugs. [Conclusion] There is possibility of A. cantonensis infection by food source and prevention measures should be carries out.