Efficacy of a Dentifrice Containing 5.53% Potassium Citrate on Dentinal Hypersensitivity

Objective:To evaluate the efficacy of a dentifrice containing 5.53% potassium citrate(test)on dentinal hypersensitivity compared with the fluoride dentifrice(control)over a 4-week period.Methods:The study design was a randomized,double-blinded,controlled clinical trial.65 subjects were randomly divided into two groups,with 33being given a 5.53% potassium citrate dentifrice(treated group)and the other 32 afluoride dentifrice(control group).Both groups were instructed to brush their teeth twice a day.An air blast stimulus was used to measure pain using a VAS scale.The efficacy of dentifrice containing 5.53% potassium citrate on dentinal hypersensitivity was tested using the nonparametric Mann-Whitney U-test.Results:The VAS(baseline=63.1,4weeks=46.2) was significantly reduced over the 4weeks period in the test group(P0.05).After 4weeks,VAS in the test group was lower than that in the control group,there was a statistically significant difference.83.9% of subjects in the test group claimed the test dentifrice significantly relieve dentinal hypersensitivity.77.4% were willing to continue to use the test product for anti-dentinal hypersensitivity.Conclusion:The study demonstrates that the dentifrice containing 5.53% potassium citrate effectively reduces dentinal hypersensitivity.