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2007•Chinese Journal of Clinical NeurosciencesRequires access

Neurogenesis in the Adult Subventricular Zone

Chun Zhong

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Abstract

The neurogenesis in subventricular zone(SVZ), which is located in the lateral wall of the lateral ventricle, is observed throughout the lifetime in mammalian. The studies suggested neurogenesis could be stimulated further by pathological processes and newly generated neurons might be capable of replacing loss cells in neurological diseases. This paper overviewed the source, composition and architecture of the adult SVZ neurogenesis and the progress of the correlationship between SVZ neurogenesis and neurodegenerative diseases in the recent years.

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What this paper is about

The neurogenesis in subventricular zone(SVZ), which is located in the lateral wall of the lateral ventricle, is observed throughout the lifetime in mammalian. The studies suggested neurogenesis could be stimulated further by pathological processes and newly generated neurons might be capable of replacing loss cells in neurological diseases. This paper overviewed the source, composition and architecture of the adult SVZ neurogenesis and the progress of the correlationship between SVZ neurogenesis and neurodegenerative diseases in the recent years.

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Available abstract

The neurogenesis in subventricular zone(SVZ), which is located in the lateral wall of the lateral ventricle, is observed throughout the lifetime in mammalian. The studies suggested neurogenesis could be stimulated further by pathological processes and newly generated neurons might be capable of replacing loss cells in neurological diseases. This paper overviewed the source, composition and architecture of the adult SVZ neurogenesis and the progress of the correlationship between SVZ neurogenesis and neurodegenerative diseases in the recent years.

Key concepts: Neurogenesis, Subventricular zone, Neuroscience, Lateral ventricles, Biology, Neural stem cell, Stem cell, Cell biology

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