Research on the Relationship between Carotid Atherosclerosis and Progressive Ischemic Stroke

Objective To study the relationship between carotid atherosclerosis and progressive ischemic stroke. Methods Doppler ultrasonography in 282 patients with acute ischemic stroke. And the characteristics of carotid atheroscherosis was compard to patients with or Without progressive ischemia stroke. Results Of all the 282 patients with ischemic stroke,67 patients(23.8%)were progressive during stroke acute period. 25(45.4%)of 55 patients with severe carotid atheroscherosis,24(50.0%)of 48 patients with carotid high-grade stenosis and 23(53.4%)of 43 patients with carotid ulcerated plaque. The frequency of progressive ischemic stroke in these patients was significantly higher than those patients without or with mild carotid atheroscherosis. The logistic regression analysis showed that the severity of carotid atheroscherosis,stenosis,ulcerated plaque were positively related to the progressive ischemic stroke.Conclusion There might be a positive relationshop between carotid atheroscherosis and ischemic stroke in evolytion.The severity of carotid atheroscherosis may be a risk predictor in stroke evolution.