XStrain~(TM) echocardiography evaluation of regional and global left ventricular systolic function in uremia patients

Objective To explore the feasibility of XStrainTMin evaluating regional and global systolic function of left ventricle(LV)in uremic cardiomyopathy patients.Methods A total of 28 uremic patients(group A,normal LV,n=12;group B,LV hypertrophy,n=16)and 16 normal subjects(group C)were enrolled.The dynamic images of apical four chamber view,apical long axis view and two chamber view by thoracic echocardiography were obtained and stored.The original data was recorded and analyzed by using a novel off-line XStrainTManalysis software.The longitudinal/transversal systolic strain and strain rate in 16 segments were acquired.Global strains were calculated by averaging segmental strains.The statistical analysis was performed.Results Compared with group C,the longitudinal systolic strains and strain rates except for posterior septal of mid segments,the transversal systolic strains except for anteroseptal and posteroseptal wall of mid segments,the transversal systolic strain rates were lower in all segments,which in group B were also lower than those of group A(all P0.05).Compared with group C,the global longitudinal and transversal systolic strains were lower(all P0.05).Conclusion XStrainTMcan display clearly and comprehensively LV myocardium,evaluate the LV systolic function,and quantitatively assess the regional and global systolic function in uremic patients.