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Reaction Study of Dibromo-tropolone and Aryl-hydrazine,Hydrazine Hydrate,Hydroxylamine and NaN_3

Wentao Gao

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Abstract

3-acetyltropolone was substituted by bromine at ice-water temperature in the presence of acetic acid to give 3-acetyl-5,7-dibromotroplone(1).Then compound(1) was reacted with aryl-hydrazine,hydrazine hydrate,hydroxylamine and NaN3,respectively to get compounds 2a-d,3,4 and 5.The purities of the compounds were within 91.7-100%.And the structures of the compounds were confirmed by IR,HNMR,MS data.

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3-acetyltropolone was substituted by bromine at ice-water temperature in the presence of acetic acid to give 3-acetyl-5,7-dibromotroplone(1).Then compound(1) was reacted with aryl-hydrazine,hydrazine hydrate,hydroxylamine and NaN3,respectively to get compounds 2a-d,3,4 and 5.The purities of the compounds were within 91.7-100%.And the structures of the compounds were confirmed by IR,HNMR,MS data.

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Available abstract

3-acetyltropolone was substituted by bromine at ice-water temperature in the presence of acetic acid to give 3-acetyl-5,7-dibromotroplone(1).Then compound(1) was reacted with aryl-hydrazine,hydrazine hydrate,hydroxylamine and NaN3,respectively to get compounds 2a-d,3,4 and 5.The purities of the compounds were within 91.7-100%.And the structures of the compounds were confirmed by IR,HNMR,MS data.

Key concepts: Hydrazine (antidepressant), Hydrate, Hydroxylamine, Chemistry, Tropolone, Bromine, Acetic acid, Aryl

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