Medication Rule for Treatment of Essential Hypertension in South of Five Ridges:An Analysis of Traditional Chinese Medical Literature

Objective To explore the medication rule of Chinese herbal medicine for treatment of essential hypertension(EH)in the South of Five Ridges,and to provide valuable evidence for EH clinical practice.Methods Frequency analysis method was used to explore the medication rule of Chinese herbal medicine for treatment of EH after analyzing 102 associated traditional Chinese medical reports for treatment of EH in the South of Five Ridges,which were published from 1994 to 2009.Results(1)The following Chinese herbs were used for EH frequently in decreasing sequence,and they were herbs for tonifying deficiency,herbs for calming liver and subsiding wind,herbs for activating blood,herbs for clearing heat,herbs for promoting urination and draining dampness,herbs for tranquilizing by nourishing the heart,herbs for for relieving exterior syndrome and herbs for regulating qi.The frequently-used single herb was as follows(in decreasing sequence): RadixAchyranthisBidentatae,Poria,RadixPaeoniaeAlba,RamulusUncariaecumUncis,Cortex Eucommiae,Concha Haliotidis,Rhizoma Gastrodiae,Flos Chrysanthemi,Herba Taxilli.(2)The application of Chinese herbal recipe for the syndromes was shown as Longdan Xiegan Decoction and Tianma Gouteng Decoction for the syndrome of hyperactive liver fire,Qiju Dihuang Pills,Tianma Gouteng Decoction and Zhengan Xifeng Decoction for the syndrome of yang hy peractivity due to yin deficiency,Banxia Baizhu Tianma Decoction,Wendan Decoction and Erchen Decoction for the syndrome of abundance of phlegm and dampness,Erxian Decoction,Yougui Pills,and Jinkui Shenqi Pills for the syndrome of yin-yang deficiency,Tianma Gouteng Decoction,Lingjiao Gouteng Decoction,and Shijue Muli Decoction for the syndrome of hyperactive liver yang.The medication of single herb for the syndromes was shown as Radix Scutellariae,Fructus Gardeniae,Ramulus Uncariae cum Uncis,Spica Prunellae,Radix Gentianae,and Flos Chrysanthemi for hy peractive liver fire syndrome,Radix Scutellariae,Radix Paeoniae Alba,Ramulus Uncariae cum Uncis,Fructus Corni,and Radix Rehmanniae Preparata for the syndrome of hyperactive yang due to yin deficiency,Rhizoma Pinelliae,Poria,Pericarpium Citri Reticulatae,and Rhizoma Gastrodiae for the syndrome of abundance of phlegm and phlegm,Fructus Corni,Radix Rehmanniae Preparata,Cortex Eucommiae,Radix Achyranthis Bidentatae,Herba Epimedii for the syndrome of yin-yang deficiency,Ramulus Uncariae cum Uncis,Radix Achyranthis Bidentatae,Concha Haliotidis,Radix Paeoniae Alba,and Rhizoma Gastrodiae for the syndrome of hyperactivitity of liver yang.Conclusion The analysis of recent 15-year Chinese medical reports for treatment of EH in the South of Five Ridges showed that the therapeutic principles are based on the pathogenesis of deficiency,phlegm,stasis and fire,and nourishing liver and kidney,regulat ing yin and yang,strengthening spleen to dampness are the main principles for treating EH by traditional Chinese Medicine.