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2008•Chinese Journal of OsteoporosisRequires access

Matrix gla protein and postmenopausal osteoporosis

Wang Pingfang

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Abstract

Matrix Gla protein(MGP) is the inhibitor of calcification of arteries and cartilage to be characterized in vivo.MGP might inhibit matrix mineralization.Evidences are accumulating that there is a close relationship between bone and vascular calcification and both organs are regulated by common factors in elderly women.Artery calcification inhibiting of MGP is linked to bone resorption.The relationship between MGP and postmenopausal osteoporosis was reviewed briefly in this article.

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What this paper is about

Matrix Gla protein(MGP) is the inhibitor of calcification of arteries and cartilage to be characterized in vivo.MGP might inhibit matrix mineralization.Evidences are accumulating that there is a close relationship between bone and vascular calcification and both organs are regulated by common factors in elderly women.Artery calcification inhibiting of MGP is linked to bone resorption.The relationship between MGP and postmenopausal osteoporosis was reviewed briefly in this article.

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Available abstract

Matrix Gla protein(MGP) is the inhibitor of calcification of arteries and cartilage to be characterized in vivo.MGP might inhibit matrix mineralization.Evidences are accumulating that there is a close relationship between bone and vascular calcification and both organs are regulated by common factors in elderly women.Artery calcification inhibiting of MGP is linked to bone resorption.The relationship between MGP and postmenopausal osteoporosis was reviewed briefly in this article.

Key concepts: Matrix gla protein, Calcification, Osteoporosis, Bone matrix, Postmenopausal women, Bone resorption, In vivo, Endocrinology

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