2004•Chinese Journal of Clinical HepatologyRequires access

The relationship between serum leptin levels and the levels of fibrosis marks in patients with hepatitis B.

Rao Wei-qiang

Abstract

Study the relationship between the serum leptin levels of patients with chronic Hepatitis B (CHB) and liver cirrhosis, The serum leptin levels of 45 patients with CHB and 41 control subjects were determined by means of radioimmunoassay. We found the leptin levels of patients with CHB was higher than the control (7.63±2.19) ng/ml vs (3.82±1.09) ng/ml (P0.001), moreover the ratio of leptin to BMI was the same result. (0.28±0.07 vs 0.15±0.03,P0.001). There were positive correlation between the serum leptin levels and the levels of LN、HA、PCⅢ and ⅣC.

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Key concepts: Leptin, Radioimmunoassay, Internal medicine, Cirrhosis, Chronic hepatitis, Medicine, Endocrinology, Liver fibrosis