Study on Changes of Systemic Immune Function of Chicken Infected with Chicken Anemia Virus
Li GuangXing
Abstract
Li GuangXing
Abstract
The one-day-old chicken were infected with chicken anemia.At different period after infection the experimental chickens were undertaken to study number of T cells and B cells as well as the content of IgG,IgM,IgA in the serum,the number of IgG +,IgM +,IgA + antibody producing cells and T cells along with the T and B cells proliferative response in thymus,Bursa Fabricius and spleen,and the inductive activity of interlukine-2(IL-2) and interferon(IFN) in thymus and spleen.The results incdicated that the systemic cellular and humoral immunity and immunoreguration decreased markedly in comparison with the control chickens.
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The one-day-old chicken were infected with chicken anemia.At different period after infection the experimental chickens were undertaken to study number of T cells and B cells as well as the content of IgG,IgM,IgA in the serum,the number of IgG +,IgM +,IgA + antibody producing cells and T cells along with the T and B cells proliferative response in thymus,Bursa Fabricius and spleen,and the inductive activity of interlukine-2(IL-2) and interferon(IFN) in thymus and spleen.The results incdicated that the systemic cellular and humoral immunity and immunoreguration decreased markedly in comparison with the control chickens.
Key concepts: Spleen, Bursa of Fabricius, Immune system, Antibody, Immunology, Biology, Humoral immunity, Anemia