Retrospective Analysis of Endometrial Carcinoma Treated by Different Therapeutic Modalities

Objective To anmlysis the therapeutic effects of different remedis in patients with endometrial carcinoma.Methods Total of 336 patients with metracarcinoma underwent 4 different treatments:①operation only 95 cases;②operation and complemental radiotherapy 105 cases;③radiotherapy only 55 cases;④chemotherapy and progesterone therapy 81 cases.Then they were followed up for 5 years and more.Results The 5 year survival rates of operation were 78%,60%,17 3% in stage Ⅰ,stage Ⅱ and stage Ⅲ-Ⅳ respectively,for operation and complemental radiotherapy,They were 73%,59 5%,50%,for radiotherapy,they were 37 5%, 18% and 0%;for chemotherapy and progesterone thenapy,they were 37 5%,17.6% and 5%.There were no difference between operation group and operation plus radiotherapy in patients with stage Ⅰ and stage Ⅱ ( P 0 005).However the 5 year survival rates were significantly higher in operation plus complemental radiotherapy than those only received operation in stage Ⅲ,stage Ⅳ patients ( P 0 01).There were no difference between radiotherapy and drug therapy in stage Ⅰ and stage Ⅱ ( P 0 05).But the 5 year survival rates were a ciltle higher in drug therapy than those only received radiotherapy in stage Ⅲ and stage Ⅳ.Conclusion Operation is the best choice for the patients of early middle stage,and complemental radiotherapy is better drug therapy or radiotherapy is fit for the patients who can't be operated on or on addvanced stage.