Application to determination of peak expiratory flow rate in asthma in children

Objective:To determine the regression equation of peak expiratory flow rate(PEFR)and adapte to the children of Baotou.To explore the value of PEFR in the diagnosis,classification and stepladder like treatment of asthma.Methods:1237 children aged 5 to 13 in the Baotou area were selected as the healthy group;26 cases of children of asthma in stages of attack and restoration stages were chosen as the diseased group.Determination PEFR with pocket peak flow instrument and the variation of the PEFR and the ration of actual value to precalculating value in diseases group.Results:(1)It was found that regression equation of PEFR in healthy group,which can provide the objective standard for detecting the air flow's restriction;(2)overall the study demonstrated that PEFR in the attacking stage of children with asthma decreased obviously and viriation rate of PEFR increased,actual value to the precalculating value was lower than 80%,all the index above mentioned in the stage of attack and restoration had higher significace(P0 01).Conclusions:(1)The regression equation of PEFR in healthy group is as follows,PEFR of boys=2 3X 1+1 7X 2+6 1X 3-177.PEFR of girls=2 2X 1+1 8X 2+3 8X 3-156[X 1 height(cm),X 2 weight(kg),X 3 year].(2)Conclusion is that PEFR and the variation rate of PEFR and the ratio of actual value to precalculating value is useful,which help the treatment and control of asthma according to the GINA project.