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The clinical significance of IL-6 and TNF-α levels in serum of the serious cases of hand-foot-and-mouth disease(HFMD) caused by enterovirus 71 in children

XU Bo-hua

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Abstract

Objective To study the clinical significance of IL-6 and TNF-α levels in serum of the serious cases of HFMD caused by enterovirus 71 in children.Methods IL-6 and TNF-α were determined using ELISA in 30 cases with the serious cases of HFMD and 15 children saved as controls.Results The levels of IL-6 and TNF-α in serum were much higher than that of the controls(P 0.01).Conclusion IL-6 and TNF-α not only have anti-viral effect,but also involve in the pathological process in the serious cases of HFMD caused by enterovirus 71 in children.

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What this paper is about

Objective To study the clinical significance of IL-6 and TNF-α levels in serum of the serious cases of HFMD caused by enterovirus 71 in children.Methods IL-6 and TNF-α were determined using ELISA in 30 cases with the serious cases of HFMD and 15 children saved as controls.Results The levels of IL-6 and TNF-α in serum were much higher than that of the controls(P 0.01).Conclusion IL-6 and TNF-α not only have anti-viral effect,but also involve in the pathological process in the serious cases of HFMD caused by enterovirus 71 in children.

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Available abstract

Objective To study the clinical significance of IL-6 and TNF-α levels in serum of the serious cases of HFMD caused by enterovirus 71 in children.Methods IL-6 and TNF-α were determined using ELISA in 30 cases with the serious cases of HFMD and 15 children saved as controls.Results The levels of IL-6 and TNF-α in serum were much higher than that of the controls(P 0.01).Conclusion IL-6 and TNF-α not only have anti-viral effect,but also involve in the pathological process in the serious cases of HFMD caused by enterovirus 71 in children.

Key concepts: Medicine, Enterovirus 71, Hand-foot-and-mouth disease, Enterovirus, Clinical significance, Pathological, Disease, Hand foot mouth disease

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The clinical significance of IL-6 and TNF-α levels in serum of the serious cases of hand-foot-and-mouth disease(HFMD) caused by enterovirus 71 in children — Research Paper | ScholarLens