Clinical features of acute myocardial infarction in the young and coronary angiography analysis

Objective To explore the features of the clinical and coronary angiography in the young patients(≤45years)with acute myocardial infarction(AMI).Methods One hundred and two young AMI patients(≤45years old,young group)and 100 elderly AMI patients(60-75 years old,elderly group)from the Department of Cardiology in the Second Hospital of Tianjin Medical University were enrolled in the study.The risk factors,induced factors,clinical manifestations,biochemical indicators,coronary angiography findings,complications and prognosis were analyzed in two groups.Results Male,smoking history,drinking history,family history of premature coronary heart disease,high triglyceride(TG),low high density lipoprotein cholesterol(HDL-C)and high uric acid(UA)were the risk factors in young group.The hypertension history,diabetes history,high fasting blood glucose were more common in elderly group.The young group had a clear incentive for 52.0%(53/102),elderly group had a clear incentive for 28.0%(28/100),the former was higher than that of the latter(P 0.01).The young group 85.3%(87/102),elderly group78.0%(78/100)had typical angina pectoris,there were no significant differences between two groups.The chest tightness in young group 31.4%(32/102)appeared significantly higher than that of elderly group of 16.0%(16/100)(P 0.05).Coronary angiography showed there were no significant difference in infarction related artery,thrombus burden between two groups,but AMI in young group occurred in the anterior descending artery for 55.9%(57/102);single vessel disease and local lesions of AMI were more frequent in the young group(P0.01);Gensini lesion score was lower(P 0.05).Compared with the elderly group,the young group had fewer complications,especially arrhythmia and heart failure,and lower mortality in one week(P 0.01).Conclusion The main risk factors of AMI young patients were male,smoking,drinking,family history of premature coronary heart disease,high TG,low HDLC and high UA.Tiredness and drinking were the main inducing factors.Single vessel disease,localized lesions were most common in young AMI patients,while their Gensini score,the complications and the mortality were lower or less.