2012•Chinese Journal of Experimental and Clinical Infectious DiseasesRequires access
Carbapenemas gene in multi-drug resistant acinetobacter baumannii
Zong Gui-zhe
Open publisher page 0 citations
Abstract
Objective To investigate the presence of carbapenemas gene in multi-drug resistant acinetobacter baumannii isolated from our hospital,and to provide scientific basis for rational application of antibiotics and control of nasocmmial infection. Methods Drug susceptibility of the strains were detected by microdilution method and disk diffusion method,and the presence of OXA23-type carbapenemas genes were detected by PCR,and part of the positive products selected by PCR were sequenced. Among the 46 multi-drug resistant acinetobacter baumannii isolated from our hospital,gene sequencing was performed in some positive strains. Results Among the 46 strains of multi-drug resistant acinetobacter baumannii,41 ( 89. 1%) strains carried OXA23,6 ( 13%) strains carried IMP,while all the other genes were negative. Conclusions Carbapenems genes of multi-drug resistant acinetobacter baumannii isolated from our hospital was mainly OXA23-type gene and secondly was IMP gene.