Application of intrathecal combination with low-dose Sufentanil in elder patients

【Objective】To evaluate the anesthesia effect and side-effect of intrathecal Bupivacaine combination with low-dose Sufentanil in elder patients. 【Method】60 elder patients,ASA Ⅱ～Ⅲ,at age 70～90,were randomly allocated into two groups n =60:group L (only Bupivacaine 7.5 mg),group LS (Bupivacaine 4.5 mg with Sufentani 15 μg). All patients received 6.7% glucose hyperbaric mix-solusion to a total amount of 1.5 ml for spinal anesthesia. Data obtained from this study included the time to onset,the highest level and duration of sensory block,and side effects were also recorded.【Results】The demographic data including age,height,body weight,ASA physical status were not significantly different between the two groups. Compared with group L,group LS has represented the rapid onset and the prolonged duration. The mean plane of motor block was higher in group L than in group LS. The incidence of hypotension and nausea were higher in group L than in group LS.【Conclusions】The addition of sufentanil 5μg to bupivacaine 4.5 mg provides adequate analgesia with fewer side-effects in elderly patients when compared with bupivacaine 7.5 mg alone during spinal anesthesia.