Clinical research of ERCP biliary stent placement for treating the patients with malignant biliary obstruction

[Objective] To investigate the clinical effects of endoscopic retrograde cholangiopancreatography (ERCP) biliary stent placement for treating the patients with malignant biliary obstruction. [Methods] The clinical data of 60 cases with malignant biliary obstruction was retrospectively analyzed from August 2008 to February 2011. 60 patients were divided into two groups by surgical treatment, the biliary stent placement (stent group, 32 cases) and surgical palliation groups (conventional group, 28 cases). The conventional group was treated with conventional surgical palliative surgery, stent group was treated by ERCP biliary stent placement. The liver function levels of the two groups in preoperative and postoperative 1 week were detected, the occurrence of complications was observed, ant the survival time of patients was recorded in the follow-up period. [Results] The stent group's patients were successful stent placement, the success rate was 100%. After surgery, the liver function of the two groups were significantly improved, the liver function (TB, ALT, AST, ALP, GGT) were significantly lower compared with the preoperative levels, the different was significant (P 0.05), and the liver function (TB, ALT, AST, ALP, GGT) levels of the stent group was significantly reduced compared with the conventional group levels, the different was significant (P 0.05); The rate of postoperative complication of stent group was 15.6%, the conventional group was 50.0%, the compared the different was significant (P 0.05); The postoperative survival rate and average survival time were no significant difference in the two groups (P 0.05). [Conclusion] The ERCP biliary stent placement is superior to traditional surgery, and it is a better method for treating the patients with malignant biliary obstruction. The surgical has high success rate and fewer complications, it is worthy of clinical application.