Studies on the anti-bacteria effect of fructus forsythia and folium forsythia in vitro

To compare the bacteriostatic activity of green fructus forsythia,ripe fructus forsythia and folium forsythia,to search the best bacteriostatic parts and the effective antimicrobial component of fructus forsythia.Using the plating method and the inhibition zone diameter comparison method.The results showed that all the extracts from fructus forsythia had obvious effect of growth inhibition on Escherichia coli,Staphylococcus aureus and Bacillus Subtilis,and didn't have any inhibitory effects on Saccharomyces cerevisiae,Aspergillus flavus and Penicillium chrysogenum.The bacteriostatic effect of folium forsythia was as strong as green fructus forsythia,and the inhibitory effect of folium forsythia was stronger than that of ripe fructus forsythia.the results also showed that the extract of green fructus forsythia extracted by 40% ethanol was the effective bacteriostatic parts.Forsythoside A may be the main activity bacteriostatic component;the folium forsythia had obvious effect of growth inhibition on bacteria,and had good development prospects.