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2001•Academic Journal of Second Military Medical UniversityRequires access

The application of microelectrode recording during operation for Parkinson's disease

Zhou Xiao

Open publisher page 1 citations

Abstract

Objective: : To explore the effects of stereotact ic microelectrode recording surgery for Parkinson's disease. Methods: Three hundred and fifty patients with Parkinson's disease received palli dotomy and/or thalamotomy from Apr,1999 to Feb, 2001. Of these patients, 278 und erwent a unilateral pallidotomy, 35 underwent thalamotomy, 15 underwent simultan eous unibilateral pallidotomy and thalamotomy, 11 underwent simultaneous bilater al pallidotomy,11 underwent staged bilateral pallidotomy or thalamotomy. The UPD RS scale was used to assess patients in on- and off -drug conditions b efore and after operation. Results: After operation Schwab and E ngland of daily living scale improved by 29.8% in off status and by 25.9% in on status, the UPDRS scale improved by 57.3% in off status and by 33.4% in on status. Conclusion: Pallidotomy is much more effectiv e than thalamotomy for Parkinson's patients with tremor.The combination of palli dotomy and thalamotomy is safe and effective for Parkinson's disease.

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Objective: : To explore the effects of stereotact ic microelectrode recording surgery for Parkinson's disease. Methods: Three hundred and fifty patients with Parkinson's disease received palli dotomy and/or thalamotomy from Apr,1999 to Feb, 2001. Of these patients, 278 und erwent a unilateral pallidotomy, 35 underwent thalamotomy, 15 underwent simultan eous unibilateral pallidotomy and thalamotomy, 11 underwent simultaneous bilater al pallidotomy,11 underwent staged bilateral pallidotomy or thalamotomy. The UPD RS scale was used to assess patients in on- and off -drug conditions b efore and after operation. Results: After operation Schwab and E ngland of daily living scale improved by 29.8% in off status and by 25.9% in on status, the UPDRS scale improved by 57.3% in off status and by 33.4% in on status. Conclusion: Pallidotomy is much more effectiv e than thalamotomy for Parkinson's patients with tremor.The combination of palli dotomy and thalamotomy is safe and effective for Parkinson's disease.

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Available abstract

Objective: : To explore the effects of stereotact ic microelectrode recording surgery for Parkinson's disease. Methods: Three hundred and fifty patients with Parkinson's disease received palli dotomy and/or thalamotomy from Apr,1999 to Feb, 2001. Of these patients, 278 und erwent a unilateral pallidotomy, 35 underwent thalamotomy, 15 underwent simultan eous unibilateral pallidotomy and thalamotomy, 11 underwent simultaneous bilater al pallidotomy,11 underwent staged bilateral pallidotomy or thalamotomy. The UPD RS scale was used to assess patients in on- and off -drug conditions b efore and after operation. Results: After operation Schwab and E ngland of daily living scale improved by 29.8% in off status and by 25.9% in on status, the UPDRS scale improved by 57.3% in off status and by 33.4% in on status. Conclusion: Pallidotomy is much more effectiv e than thalamotomy for Parkinson's patients with tremor.The combination of palli dotomy and thalamotomy is safe and effective for Parkinson's disease.

Key concepts: Pallidotomy, Thalamotomy, Parkinson's disease, Medicine, Surgery, Anesthesia, Disease, Deep brain stimulation

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