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2006•PubMedRequires access

[Single nucleotide polymorphisms of slow troponin T gene in Han ethnic population from Northern China].

Chunyan Xu, Yang Hu, Haiping Liu

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Abstract

AIM: To analyze the distribution of single nucleotide polymorphisms in Han ethnic population from Northern China. METHODS: Allele frequencies in a sample of healthy Chinese Hans (n = 204) were determined by polymerase chain reactions followed by restriction analyses with specific endonucleases. RESULTS: The SNP 27916722 A/C in exon 11 from the NCBI database was not detected in this population. And there were significant differences between the allele frequencies of the SNPs (27930097 C/G and 27920978 C/T) in Han ethnic population from Northern China and those in the NCBI. CONCLUSION: It is suggested that the SNPs of sTnT are different in different ethnic populations.

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What this paper is about

AIM: To analyze the distribution of single nucleotide polymorphisms in Han ethnic population from Northern China. METHODS: Allele frequencies in a sample of healthy Chinese Hans (n = 204) were determined by polymerase chain reactions followed by restriction analyses with specific endonucleases. RESULTS: The SNP 27916722 A/C in exon 11 from the NCBI database was not detected in this population. And there were significant differences between the allele frequencies of the SNPs (27930097 C/G and 27920978 C/T) in Han ethnic population from Northern China and those in the NCBI. CONCLUSION: It is suggested that the SNPs of sTnT are different in different ethnic populations.

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Available abstract

AIM: To analyze the distribution of single nucleotide polymorphisms in Han ethnic population from Northern China. METHODS: Allele frequencies in a sample of healthy Chinese Hans (n = 204) were determined by polymerase chain reactions followed by restriction analyses with specific endonucleases. RESULTS: The SNP 27916722 A/C in exon 11 from the NCBI database was not detected in this population. And there were significant differences between the allele frequencies of the SNPs (27930097 C/G and 27920978 C/T) in Han ethnic population from Northern China and those in the NCBI. CONCLUSION: It is suggested that the SNPs of sTnT are different in different ethnic populations.

Key concepts: Single-nucleotide polymorphism, Genetics, SNP, Allele frequency, Allele, Ethnic group, Polymorphism (computer science), Population

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[Single nucleotide polymorphisms of slow troponin T gene in Han ethnic population from Northern China]. — Research Paper | ScholarLens