Efficacy and Safety of Tirofiban for Percutancous Coronary Intervention in Patients with Acute Myocardial Lnfarction

Objective To evaluate the efficacy and safety of tirofiban for percutaneous coronary intervention in patientswith acute myocardial infarction.Methods 80 patients diagnosed AMI were randomly divided into study group(n=40)and the control group(n=40).The coronary TMP flow of IRA after PCI,major adverse cardiac events(MACE)rates within 24 hours and 30 days,bleeding rates were analyzed and compared between the two groups.Results Compared with control group,the patients treated with tirofiban were significantly better TIMI3 flow degree(P0.05)The tirofiban group decreased MACE in 24 hours and 30 days after PCI(P0.05).The complication of bleeding rate showed higher in the tirofiban group,but there was not statistical significant in between two groups(P0.05).Conclusion The results suggest that tirofiban is a safe and moreefficacious therapy for the patients with AMI during PCI compared with conventional therapy,which can improve the situation of myocardial reperfusion and degree the MACE.