ScholarLens Back to search
2012•Modern Agricultural Science and TechnologyRequires access

Determination of Sulfonamide in Beef by High Performance Liquid Chromatography-tandem Mass Spectrometry

Qian Li

Open publisher page 0 citations

Abstract

A HPLC-MS/MS method for determination of 7 sulfonamides residues in beef was made in the paper.The sample was extracted with acetonitrile and anhydrous sodium sulfate,purified and defatted with n-hexane,then detected by high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS).The results showed that calibration curves for 7 sulfonamides residues all had good linear relationships with correlation coefficients not less than 0.998.The spiked recoveries at three concentrations were ranged from 92.5% to 100.6%,with relative standard deviations of 2.0%~4.5%.The limits of detection were in the range of 1.0~4.5 μg/L.It was an effective method which fitted for the sulfonamides residues analysis and had high accuracy,precision and sensitivity.

About this research paper

What this paper is about

A HPLC-MS/MS method for determination of 7 sulfonamides residues in beef was made in the paper.The sample was extracted with acetonitrile and anhydrous sodium sulfate,purified and defatted with n-hexane,then detected by high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS).The results showed that calibration curves for 7 sulfonamides residues all had good linear relationships with correlation coefficients not less than 0.998.The spiked recoveries at three concentrations were ranged from 92.5% to 100.6%,with relative standard deviations of 2.0%~4.5%.The limits of detection were in the range of 1.0~4.5 μg/L.It was an effective method which fitted for the sulfonamides residues analysis and had high accuracy,precision and sensitivity.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

A HPLC-MS/MS method for determination of 7 sulfonamides residues in beef was made in the paper.The sample was extracted with acetonitrile and anhydrous sodium sulfate,purified and defatted with n-hexane,then detected by high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS).The results showed that calibration curves for 7 sulfonamides residues all had good linear relationships with correlation coefficients not less than 0.998.The spiked recoveries at three concentrations were ranged from 92.5% to 100.6%,with relative standard deviations of 2.0%~4.5%.The limits of detection were in the range of 1.0~4.5 μg/L.It was an effective method which fitted for the sulfonamides residues analysis and had high accuracy,precision and sensitivity.

Key concepts: Chromatography, Chemistry, Mass spectrometry, Tandem mass spectrometry, High-performance liquid chromatography, Calibration curve, Anhydrous, Liquid chromatography–mass spectrometry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Determination of Sulfonamide in Beef by High Performance Liquid Chromatography-tandem Mass Spectrometry — Research Paper | ScholarLens