Drug resistance of pathogens in urinary System infection

Objective:To know the present status and drug resistance of pathogens in urinary system infection.Methods:A total of 380 pathogen strains in urinary system infection from inpatients and outpatients from 2001 to 2004 were identified. The drug resistance test was preformed by Kirby-Bauer method.The ESBLs-preducing Escherichia coli was detected.Results:Escherichia coli rated the top one(50.0%),the next was Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Enterobacter cloacae, Klebsiella pneumoniae. The result of drug resistance suggested that gram-negative and gram-positive bacteria were resistant to several antibiotics,but the former was still sensitive to imipenem (94.4%),the latter still sensitive to teicoplanin and vancomycin (100.0%). Drug resistance of ESBLs-producing E.coli was more serious than that of non- ESBLs-producing strains to 11 antibitics.Conclusion:E.coli is the main pathogen in urinary infection. Rational use of antibiotics should be carried out according to urine culture results.