Clinical analysis on 42 childish cases of precocious puberty

Objective To summarize the clinical features of precocious puberty in order to improve clinical understanding of pediatric physicians.Methods The clinical data of 42 cases of precocious puberty in pediatric department of this hospital from January 2006 to February 2010 were retrospectively reviewed and analyzed.Results Among these 42 childish patients,19 cases suffered from precocious puberty,17 cases of pseudo precocious puberty and 6 cases of partial precocious puberty and the ratio of girls to boys was 10 : 1.Precocious puberty in majority of children was manifested as acceleration in height growth,in advance of bone age,enlargement of gonads and positive stimulation of luteinizing hormone release test(LHRH).In cases of pseudo-precocious puberty,suspicious inducing factors could be found in most of them,some of them with accerated height growth and advanced bone age,and enlargement of gonads is not obvious.LHRH stimulation test was negative.Conclusion In precocious children,girls are more prevalent than boys,precocious puberty is mostly idiopathic in girls.The majority of children with precocious puberty have related inducing factors.The determination of bone age,gonadal BUS and LHRH stimulation test are important in differential diagnosis of precocious puberty in children.