Research on the study of pregnancy-associated liver diseases and changes of placental

Placenta is the special product between the mother and the fetus and a vital organ to maintain fetal development in intrauterine nutrition.The decline in placental function can impact the fetal and lead to a variety of adverse pregnancy outcome.Pregnancy-associated liver disease including ICP(Intrahepatic cholestasis of pregnancy),HELLP(hemolysis,elevated liver enzymes,and low platelets syndromecan) and pregnancy complicated with hepatitis can cause a series of the physiological or pathological changes in placenta.This article would give the summary on its physiological and pathological mechanisms.