2002•Chinese Journal of Critical Care MedicineRequires access
Effects of hemofiltration on hemodynamics and oxygenation in patients with ARDS after severe trauma
Xiong Jian-qion
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Abstract
Objective To study the effects of hemofiltration on hemodynamics and oxygenation in patients with ARDS after severe trauma Methods 12 patients with ARDS after severe trauma were selected and treated with hemofiltration under respiratory support Hemodynamics and oxygenation were measured or calculated at scheduled intervals by use of Swan-Ganz catheters.Results Central venous pressure(CVP),mean pulmonary arterial pressure(MPAP),indices of systemic vascular resistance and pulmonary vascular resistance(SVRI,PVRI)decreased significantly,throughout the hemofiltration,PaO 2/FiO 2 increased and mean arterial pressure(MAP),pulmonary capillary wedge pressure(PCWP),heart rate(HR),cardiac index(CI),oxygen delivery(DO 2),oxygen consumption(VO 2),oxygen extraction(ExtrO 2)and intrapulmonary shunt(Qs/Ot) did not change significantly.Conclusion Continuous hemofiltration can increase PaO 2/FiO 2 and has no significant effects on hemodynamics and oxygenation.