Relation between dynamic blood pressure change and arterial compliance in subjects with normal blood pressure

Objective To study the rrelation of 21 h ABPM rhythm with crPWV and IMT in subjects with normal blood pressure.Methods Two hundred and eighty-six subjects enrolled in this study were divided into ideal blood pressure( 120/80 mm Hg) group(n = 90) and prehypertension groupCn= 196).Their 24 h ABPM,crPWV and IMT were mornitored.The 196 subjects in prehypertension group were further divided into dipper group(n= 103) and non dipper group(n = 93) according to their prehypertension parameters and their crPWV and IMT were measured.Results The 24 h systolic blood pressure,crPWV and IMT were higher in non dipper group than in dipper group(122.00±9.74 mm Hg vs 116.74±8.66 mm Hg,9.53±1.14 m/s vs 8.38±0.88 m/s,0.93±0.11 mm vs 0.81±0.12 mm,P0.05).Multiple regression analysis showed that the average nocturnal systolic pressure,nocturnal systolic pressure decreasing rate,and average nocturnal diastolic pressure were the factors influencing crPWV,while the nocturnal diastolic pressure decreasing rate,average 24 h systolic pressure,and TG were the factors influencing IMT. Conclusion The abnormal 24 h ABPM rhythm is closely related with crPWV and IMT in patients with abnormal blood pressure.Abnormal vascular structure and elastics can be observed in patients with normal blood pressure.