Experimental study on changes of microvessels in spinal cord and neuronal microenviroment of cervical spondylotic myelopathy

Objective:To discuss the microvascular change in spinal cord and neuronal microenviroment after spinal cord chronic compressed.Method:Animal models were established,spinal cord microvascular image,morphologic and biochemical methods were employed to observe the munbers of neuron,area of microcirculation of spinal cord and the expression of VEGF,NF,GFAP.Result:The munbers of neuron,microvascular area of spinal cord decreased,apoptosis cells existed and VEGF expressed,NF dissolved,GFAP was hyperplasia,neuronal microenviroment was destroied,the more compression the more destroy.