2001•Guiyang yixueyuan xuebaoRequires access
Relationship between Endothelin-1 and Cerebral Infarction
Jin Qi
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Abstract
Objective:To measure endothelin-1 in patients with acute cerebral infarction and study the relationship between endothelin-1 and cerebral infarction.Methods: We have measured endothelin-l in 57cases with acute cerebral infarction,and have made control study with 30 healthy people.Results: There is a significant difference between the two groups (U=13.45, P0.01),and ET-1 is also found related to hypertension,hyperlipemia and diabetes.Conclusion: Endothelin is one of the risk factors of cerbral infarction.Increase of endothelin-1 in plasma is associated with cerebral infarction,and seems to be involved in the pathophysiology of acute cerebral infarction.