PATHOGENS AND THEIR DRUG RESISTANCE OF BACTERIA INDUCING CHEST HOSPITAL.

Objective:To investigate the distribution on the pathogens in the chest hospital and drug resistance of bacteria and the prevalence of the bacteria producing extended-spectrum β-lactamases(ESBLs).Method:K-B test was used for the antibiotics susceptivity test;the results were read based on National Committee for Clinical Laboratory Standard(NCCLS) in 1999.All ESBLs-producing strains were confirmed by the double disk test for ESBLs.Results:The hospital pathogens were mainly Gram-nagative bacilli,The first two strains were Escherichia coli and Pseudomonas aeruginosa.The resistance of bacteria were markedly increased.97 strains isolates of 891 strains Escherichia coli and Klebsiella pneumoniae were ESBLs-producing,the resistance rate of ESBLs-positive strains and MRSA was higher than ESBLs-negative and MSSA strains.Conclusion:The Gram-negative bacilli are the major pathogens isolated from hospital infection.The resistance of bacteria is increasing.It is very important to investigate the hospital pathogens and drug susceptibility of bacteria.The monitor should be enhanced to give suggestions to rational use of antibiotics.