A coutrol study on Aripiprazole versus Risperidone in the treatment of male Schizophrenic

Objective To compare adverse events of Aripiprazole and Risperidone in the treatment of male Schizophrenic.Methods 60 male Schizophrenic were randomly divided into two groups for 8 weeks.One group was treated with Aripiprazole,another with Risperidone.Side effects were evaluated with treaments emergant symptom scale before and after 2、4、6、8 week's treatment respectively.At the same time,the serum prolaction levels were examined,and chang of sexual function were observed before and afrer 8 weeks.Results There was no significant difference in the TESS score,but Aripiprazole group showed lower scores in extra-pyramidal symptoms,prolaction level and sexual function change.Conclusions Aripiprazole is effective drug,with slight side effects,it is beneficial for the harmony of sexual relation,so it can be as better choice for the male patients with Schizophrenia.