Fanconi syndrome with hypophosphatemic osteomalacia:a case report an literature review

Objective To review the etiologies,pathogenesis,clinical manifestations and treatment of Fanconi syndrome(FS).Methods Through revisting a case,we further discussed the clinical characteristic,diagnosis criteria and treatment of FS.Results We reported a 45 years old woman with multiple bone pain,short stature and the features of hypophosphatemic osteomalacia.Laboratory test showed hypokalemia,low-molecular-weight proteinuria,renal glucosuria,aminoaciduria and proximal renal tubular acidosis.All these accorded with the diagnosis of FS.We considered the diagnosis of secondary FS because of deficiency of congenital diseases.Conclusion The etiology of FS is various.In adults,the acquired forms are the main cause of FS.