Clinical predictors of recurrence after circumferential ablation of pulmonary vein ostia to treat atrial fibrillation

Objective:To find the independent predictors of recurrence after circumferential ablation of pulmonary vein to treat atrial fibrillation,to investigate the applicable population of the procedure.Method:Fifty-one patients with atrial fibrillation(Af) underwent CARTO mapping guided circumferential radiofrequency ablation of pulmonary vein were followed up.According to rhythm at the end of follow-up,patients were divided into sinus rhythm group(SR group) and recurrence group.The basic clinical data were compared to screening factors that affect the success rate.Multiple regression analysis was done to find the independent predictors.Result:Fifty-one patients were followed up for 5-26(11.3±7.4) month.At the end of follow-up,14 patients were recurred and were chosen as recurrence group,remainders were chosen as SR group.With a retrospective study of basic clinical data,we found that duration of Af,rate of paroxysmal Af(PAf),left atrial diameter(LAD),pre-ablation high activity C-reaction protein(hCRPp),frequency of post-ablation atrial premature beats,frequency of post-ablation atrial tachycardia,post-ablation high activity C-reaction protein(hCRPf) were significant difference between the two groups.Studied by multiple regression analysis,PAf,LAD,hCRPp,hCRPf were independent predictors of recurrence.Conclusion:PAf,LAD,hCRPp,hCRPf were independent predictors of recurrence of atrial fibrillation after circumferential ablation of pulmonary vein.