2011•Zhongguo quanke yixueRequires access

Application of Recombinant Human Growth Hormone in Idiopathic Growth Hormone Deficient Children of Anyang,Henan Province

Yanfen Duan

Abstract

Objective To assess the efficacy of recombinant human growth hormone(rhGH)in idiopathic growth hormone deficient(IGHD)children of Anyang,Henan province.Methods A prospective study including 30 children[18 boys and 12 girls,with mean age of(12.0±1.5)years and BA of(8.5±2.1)years]was carried out.The enrolled children were treated with subcutaneous injection of rhGH(0.15~0.20 U·kg-1·d-1)daily before sleep for six months.Results The mean height growth rate of the enrolled children increased from(3.56±0.78)cm/year to(9.87±2.11)cm/year(P0.01).The mean HtSDSCA increased from(-2.01±0.63)cm to(-1.72±0.58)cm.HtSDSBA increased from(0.11±0.65)cm to(0.28±1.21)cm.Conclusion rhGH appears to be effective and sate in treating growth hormone deficient(IGHD)children in Anyang,Henan province,without affecting adolescence.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: IGHD, Medicine, Human growth hormone, Growth hormone, Hormone, Recombinant DNA, Pediatrics, Internal medicine